Diagnosis of Endometrial Biopsies and Curettings by Michael Mazur, , available at Book Depository with free delivery. Diagnosis of Endometrial Biopsies and Curettings: A Practical Approach. Veli Marjoniemi. x. Veli Marjoniemi. Search for articles by this author. Department of. Generally, this should comprise a formal curetting rather than an outpatient biopsy. An external Diagnostic algorithm for examination of endometrial biopsies.

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As discussed, this is the norm with an atrophic endometrium and no focal lesion on ultrasound scan, but not a reason for repeating the biopsy.

Int J Gynecol Pathol 7 — Report of 89 cases and proposed classification. A secretory endometrium and Arias—Stella effect endometrium often shows an increase in the gland to stroma ratio and may be misdiagnosed as an endometrial hyperplasia, especially when subnuclear vacuolation is not obvious.

Accepted Nov International histological classification and typing of female genital tract tumours. Check out the top books of the year on curettints page Best Books of Kamat B R, Isacson P.

Pathology and genetics of tumours of the breast and female genital organs. Email alerts New issue alert. The glands are lined by markedly atypical nuclei, characteristic of serous neoplasia. This results in the clinician and the patient assuming that the woman is postmenopausal.

Before diagnosing an endometrial hyperplasia, it is important to exclude the many benign mimics. As with other tissues, crushed areas should not be viewed in isolation.


Diagnosis of Endometrial Biopsies and Curettings : A Practical Approach

For example, some clinicians routinely conduct a repeat biopsy when an endometrial specimen has been classified as inadequate. In many cases of postmenopausal bleeding, the patient is not actually postmenopausal but rather is perimenopausal, with a prolonged interval between periods.

Assessing the glandular architecture and cytology may be difficult, as the squamous elements can be so extensive that the underlying glandular component is almost totally obliterated.

Indeed, in the setting of chronic obstruction, squamous carcinoma of the endometrium may develop from florid squamous metaplasia.

Uterine serous carcinoma and endometrial intraepithelial carcinoma arising in endometrial polyps: The endometrial glands are positive but diiagnosis stroma is negative. In this review, dating of the endometrium will not be discussed, as this has been dealt with in detail recently. J Clin Pathol 47 — The endometrium shows proliferative activity, with cystically dilated glands of irregular sizes and shapes. The management of adenofibroma and adenosarcoma is identical, comprising hysterectomy.

Am J Pathol 66— In a simple hyperplasia, the normal gland to stroma ratio is maintained or there is slight increase.

In general, mitotic activity should be identified before diagnosing an endometrial hyperplasia. Epithelial metaplasias, especially squamous or mucinous in type, may coexist with hyperplasia or a carcinoma.

My approach to the interpretation of endometrial biopsies and curettings

Int J Gynecol Pathol 15 — Sign In Forgot password? Atypical polypoid adenomyoma Only a few comments will be made djagnosis atypical polypoid adenomyoma APAconcentrating on those diagnoxis that are likely to pertain to endometrial biopsy specimens. Briefly, five criteria must be fulfilled for a diagnosis of EIN: Am J Clin Pathol 99 — Criteria for adequacy of endometrial biopsy specimens Previously, endometrial biopsy specimens were largely obtained by dilatation and curettage carried out under general anaesthesia.


Previously, endometrial biopsy specimens were largely obtained by dilatation and curettage carried out under general anaesthesia. The following points on endometrial polyps are worthy of mention: Adenofibroma and adenosarcoma Adenofibroma, with a benign stromal component, and adenosarcoma, with a malignant one, are two of the mixed epithelial and mesenchymal mixed Mullerian tumours of the uterus.

J Clin Oncol 11 — Support Center Support Center. Epithelial metaplasias are, however, especially likely to be seen in endometrial polyps and in association with hormonal preparations. Hendrickson; Diagnosis of Endometrial Biopsies and Curettings: Hormones have varying effects on the endometrium and it is essential that the clinician supplies details to the pathologist regarding any hormone treatment.

When an endometrial biopsy is carried out for abnormal uterine bleeding, the pathologist should always consider the possibility of a polyp.